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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL12
All Species:
32.12
Human Site:
T352
Identified Species:
58.89
UniProt:
Q53G59
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53G59
NP_067646.1
568
63277
T352
S
V
E
C
L
D
Y
T
A
D
E
D
G
V
W
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
D461
L
N
S
V
E
R
Y
D
P
K
T
N
Q
W
S
Rhesus Macaque
Macaca mulatta
XP_001094324
702
77633
T486
S
V
E
C
L
D
Y
T
A
D
E
D
G
V
W
Dog
Lupus familis
XP_537119
568
63260
T352
S
V
E
C
L
D
Y
T
A
D
E
D
G
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZM0
568
63228
T352
S
V
E
C
L
D
Y
T
A
D
E
D
G
V
W
Rat
Rattus norvegicus
Q8R2H4
568
63244
T352
S
V
E
C
L
D
Y
T
A
D
E
D
G
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518122
290
31726
V80
Y
T
A
D
E
D
G
V
W
Y
S
V
A
P
M
Chicken
Gallus gallus
XP_419251
558
62467
T342
S
V
E
C
L
D
Y
T
S
D
E
D
G
I
W
Frog
Xenopus laevis
Q6NRH0
564
63190
T348
S
V
E
C
L
D
Y
T
S
E
E
D
G
V
W
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
T348
S
V
E
C
L
D
Y
T
A
D
E
D
G
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
D390
L
N
S
I
E
R
Y
D
P
Q
T
N
Q
W
S
Honey Bee
Apis mellifera
XP_397065
620
68991
D397
L
N
S
I
E
R
Y
D
P
Q
T
N
Q
W
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180470
684
75689
S462
E
E
F
N
P
K
T
S
D
W
R
S
L
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.8
80.9
99.8
N.A.
99.3
99.4
N.A.
50.3
87.1
91.5
89.7
N.A.
39.9
40.4
N.A.
40.6
Protein Similarity:
100
53.6
80.9
100
N.A.
99.8
99.8
N.A.
51
91
96.6
95.2
N.A.
57.9
57.7
N.A.
55.9
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
86.6
86.6
100
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
13.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
47
0
0
0
8
0
0
% A
% Cys:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
70
0
24
8
54
0
62
0
0
0
% D
% Glu:
8
8
62
0
31
0
0
0
0
8
62
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% K
% Leu:
24
0
0
0
62
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
24
0
8
0
0
0
0
0
0
0
24
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
24
0
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
0
0
24
0
0
% Q
% Arg:
0
0
0
0
0
24
0
0
0
0
8
0
0
0
0
% R
% Ser:
62
0
24
0
0
0
0
8
16
0
8
8
0
0
24
% S
% Thr:
0
8
0
0
0
0
8
62
0
0
24
0
0
0
0
% T
% Val:
0
62
0
8
0
0
0
8
0
0
0
8
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
8
0
0
0
24
62
% W
% Tyr:
8
0
0
0
0
0
85
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _